Skin care designed to evolve with you

Expert care from licensed Canadian clinicians.
Private, secure online care
Unlimited access to your care team
Clear medication pricing, no surprises
1M+ biomarkers tested
4.7 Trustpilot rating
500k+ rx issued
60,000+ Canadians supported
Unlimited expert care
1M+ biomarkers tested
4.7 Trustpilot rating
500k+ rx issued
60,000+ Canadians supported
Unlimited expert care
1M+ biomarkers tested
4.7 Trustpilot rating
500k+ rx issued
60,000+ Canadians supported
Unlimited expert care
1M+ biomarkers tested
4.7 Trustpilot rating
500k+ rx issued
60,000+ Canadians supported
Unlimited expert care
*Based on Science & Humans clinical care data

Enjoy beautiful, radiant skin at every stage and age

Prescription-grade hormonal skin cream
Supports skin hydration, texture, tone, and elasticity during hormonal changes.
Results from
6 - 12 months*
Format
As needed (up to 1x/day)
Strengths
Estriol 0.3%
Cost
~ $60 for 30-day supply*
Get Started
Covered under most insurance drug plans or health spending accounts (HSA).

(Re)claim care on your terms

Simple, transparent, expert-led
Step 1

Assessment

$25
Now
  • In-depth online assessment
  • If eligible, Health Canada–approved prescription issued

Step 2

Care plan

  • Automatic refills every 3 months via a licensed pharmacy with discreet delivery ($10)
  • Prescription valid for up to 1 year (4 shipments), with insurance billing where applicable
  • Your $25 S&H subscription will auto-renew after 1 year

*Cost of medication is an additional charge. If your care plan is not approved, you may be eligible for a refund. Cancel subscription anytime.
If your care plan is not approved, you may be eligible for a refund. Cancel subscription anytime.

(Re)ly on experts

Your dedicated medical team
Chief Women’s Health Advisor

Dr. Kristy Prouse, MD, FRCSC (OB/GYN)

A board-certified OB/GYN with over 30 years of clinical experience and specialized training in functional and integrative hormone health, Dr. Prouse focuses on complex hormonal conditions across the female lifespan and practitioner education.
Dr. Kristy Prouse, MD, FRCSC (OB/GYN)
Chief Women’s Health Advisor
Chief Innovation Officer

Adeel Khan

Internationally recognized physician-researcher in musculoskeletal and regenerative medicine, Adeel Khan is an Assistant (Adjunct) Clinical Professor at McMaster University and the University of Toronto, with published research and global collaboration in performance medicine.
Adeel Khan
Chief Innovation Officer
Chief Men’s Health Advisor

Dr. Fady Hannah-Shmouni, MD, FRCPC, ABIM

A Clinical endocrinologist and Clinical Professor of Medicine at the University of British Columbia, specializing in endocrinology, hypertension, and genomic medicine, Dr. Hannah-Shmouni brings over a decade of experience in academic research, clinical care, and health innovation.
Dr. Fady Hannah-Shmouni, MD, FRCPC, ABIM
Chief Men’s Health Advisor
Clinician

Manuela Checedi

A board-certified Family Nurse Practitioner with over a decade of clinical experience across Canada and the U.S., Manuela specializes in hormone therapy and virtual care for women’s health, weight management, and men’s hormone health.
Manuela Checedi
Clinician
Clinician

Patrick Thibodeau

A Nurse Practitioner practicing in primary care with a focus on men’s health, Patrick specializes in testosterone replacement therapy (TRT) and age-related hormonal care. He is dedicated to evidence-based, personalized treatment that helps men restore energy, confidence, and overall vitality.
Patrick Thibodeau
Clinician
Clinician

Jodie Foster

A primary care Nurse Practitioner with a focus on hormone replacement therapy and patient-centered care, Jodie is experienced in comprehensive family practice with a commitment to accessible, relationship-based healthcare delivery.
Jodie Foster
Clinician
Clinician

Abida Dhukai

A Nurse Practitioner with over 14 years of clinical experience across emergency, primary care, critical care, and remote medicine, Abida is a clinical scientist with focused interest in cardiovascular health, exercise physiology, and hormone replacement therapy.
Abida Dhukai
Clinician
Clinician

Maria Jacob

A Nurse Practitioner with over six years of NP experience and more than 15 years in nursing, Maria’s clinical background includes primary care, mental health, and medical cannabis, with focused interest in hormone therapy and women’s health.
Maria Jacob
Clinician
Clinician

Sheena Jacob

With over 14 years of experience in primary care, chronic and complex care, and palliative medicine, Sheena holds a Master’s degree in Hospital Administration and certification in Bioidentical Hormone Replacement Therapy. She’s also a published author with a focus on women’s health.
Sheena Jacob
Clinician

Frequently asked questions

What are the benefits of using prescription-grade hormonal face cream?

The cream boosts collagen production, improves skin elasticity, hydrates, reduces fine lines, and promotes a more even skin tone by addressing hyperpigmentation.

How do I apply the face cream?

Apply a small amount to your face and neck, gently massaging until absorbed. Use it daily, preferably after cleansing and before other products.

Is the face cream suitable for all skin types?

It is generally safe for most skin types, but if you have sensitive skin or specific conditions, be sure to mention it in your intake.

Can I use other products with the face cream?

It's best to avoid using products with similar active ingredients, as the face cream's potent formula works effectively on its own. Use alongside your favourite SPF. 

How long before I see results?

You may notice improved hydration and texture within weeks. For noticeable reductions in fine lines and wrinkles, it may take a few months.

Are there any side effects?

Mild irritation or redness may occur initially. If you experience severe reactions, discontinue use and reach out to support@scienceandhumans.com.