Read in 30s...
What Are DHT Blockers and Their Role in Hair Health?
Hair thinning and hair loss can be influenced by many factors — genetics, hormones, nutrition, stress, and certain medical conditions. One hormone-related factor that has been studied in connection with hair loss is dihydrotestosterone (DHT). Some individuals explore DHT blockers as part of their hair health strategy, but it’s important to understand what they are, how they are discussed in research, and the limitations of current evidence.
Understanding DHT
Dihydrotestosterone (DHT) is a hormone derived from testosterone. Research suggests that DHT may play a role in certain types of hair loss, particularly a form known as androgenetic alopecia (commonly referred to as male or female pattern hair loss). However, not everyone with higher levels of DHT experiences hair loss, and not everyone with hair loss has elevated DHT.
What Are DHT Blockers?
DHT blockers are a category of substances that may influence how testosterone converts into DHT or how DHT interacts with hair follicles. They can be:
- Prescription medications – available only from a healthcare provider, typically prescribed after a diagnosis.
- Topical products – shampoos, conditioners, or serums that may contain ingredients marketed for scalp or hair health.
- Nutritional supplements – certain plant-based extracts are sometimes promoted for hair health, though evidence is variable.
Because the effects and safety of these options can differ widely, it’s important to consult a licensed healthcare professional before starting any DHT-blocking treatment or supplement.
Common Ingredients Found in DHT-Blocking Products
- Finasteride – available by prescription in Canada for specific conditions.
- Dutasteride – prescription only, used for certain diagnosed conditions.
- Minoxidil – a topical option available over the counter for some individuals.
- Saw Palmetto Extract – a plant-derived ingredient sometimes marketed for hair health, though clinical evidence is mixed.
- Pumpkin Seed Oil – studied in small trials, but more research is needed.
- Green Tea Extract (EGCG) – researched for various health effects, including potential impact on hair.
Things to Keep in Mind
- Effectiveness varies – Not everyone responds to DHT blockers in the same way, and results, if any, can take months.
- Potential side effects – Some prescription DHT blockers have been linked to sexual side effects, mood changes, or other health impacts.
- Underlying causes matter – Hair loss can be related to thyroid issues, nutritional deficiencies, stress, autoimmune disorders, or medication use, and may require a different approach.
When to See a Healthcare Professional
If you are experiencing hair loss, it is recommended to speak with a licensed healthcare provider who can:
- Conduct appropriate testing.
- Determine if DHT blockers are an appropriate option.
- Discuss both prescription and non-prescription treatments.
- Monitor for benefits and potential side effects over time.
DisclaimerThis content is intended for educational purposes only and should not be interpreted as medical advice. Always consult a licensed healthcare provider for personalized recommendations. |
Frequently Asked Questions
Q. How do DHT blockers work?
A. Various mechanisms are involved regarding DHT blockers. Some include the enzyme 5-alpha-reductase isoenzymes which convert testosterone to DH. Still, others enhance blood flow to the follicles of hair, promote the growth of hair and generally boost the health status of the hair. They aim to minimize the impact of DHT on hair follicles.
Q. Do DHT Blockers Prevent Hair Loss?
A. For some people, especially those with androgenetic alopecia (male and female pattern baldness), the use of DHT blockers can work in preventing hair loss as well as encouraging hair regrowth.
Q. Can women with hair loss take the DHT blocker supplements?
A. Yes, certain types of DHT blockers including Minoxidil might work well for women with hair problems. Nonetheless, most physicians would not recommend finasteride for pregnant and breastfeeding women.
Q. For how long do DHT blockers result in better performance?
A. However, the time it takes for you to see the DHT blocker’s results is not constant. For such people, hair growth could improve in as few as three months or longer periods. Using a consistent pattern of implementation, it’s all about patience.
Q. Will my results increase if I use more than one DHT blocker simultaneously?
A. Some people prefer combining various DHT blockers like minoxidil and natural supplements. Nevertheless, one should consult their doctor first before mixing various medications to be sure that they are indeed safe and helpful.
Q. Can natural remedies help with age-related hair changes?
A. For instance, some natural products would be useful to the health of hair like oils for hydration and herbal supplements. On the other hand, they are complementary and not cure-oriented compared to ageing-induced hair changes.
ReferencesMcClellan, K. J., & Markham, A. (1999). Finasteride: a review of its use in male pattern hair loss. Drugs, 57(1), 111–126. https://doi.org/10.2165/00003495-199957010-00014 Adil, A., & Godwin, M. (2017). The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. Journal of the American Academy of Dermatology, 77(1), 136–141.e5. https://doi.org/10.1016/j.jaad.2017.02.054 Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A Review of the Use of Biotin for Hair Loss. Skin appendage disorders, 3(3), 166–169. https://doi.org/10.1159/000462981 Hajhashemi, V., Rajabi, P., & Mardani, M. (2019). Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model. Avicenna journal of phytomedicine, 9(6), 499–504. https://doi.org/10.22038/AJP.2019.13463 Cho, Y. H., Lee, S. Y., Jeong, D. W., Choi, E. J., Kim, Y. J., Lee, J. G., Yi, Y. H., & Cha, H. S. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evidence-based complementary and alternative medicine : eCAM, 2014, 549721. https://doi.org/10.1155/2014/549721 Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., & Tosti, A. (2019). The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatology and therapy, 9(1), 51–70. https://doi.org/10.1007/s13555-018-0278-6 Bansal, M., Manchanda, K., & Pandey, S. S. (2012). Role of caffeine in the management of androgenetic alopecia. International journal of trichology, 4(3), 185–186. https://doi.org/10.4103/0974-7753.100096 Mysore V. (2012). Finasteride and sexual side effects. Indian dermatology online journal, 3(1), 62–65. https://doi.org/10.4103/2229-5178.93496 BinJadeed, H., Almudimeegh, A. M., Alomran, S. A., & Alshathry, A. H. (2021). A Case of Contact Allergic Dermatitis to Topical Minoxidil. Cureus, 13(1), e12510. https://doi.org/10.7759/cureus.12510 Bistas KG, Tadi P. Biotin. [Updated 2023 Jul 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554493/ Hoover E, Alhajj M, Flores JL. Physiology, Hair. [Updated 2023 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK499948/
|