Written by
Science&Humans
Written by
Science&Humans
Medically approved by
Maria Jacob
Last updated
2/26/2024 5:30:00 AM
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Testosterone is a crucial hormone for both men and women. It affects everything, from our bone density and muscle mass to our libido and mood. But when its levels drop, a series of changes can occur.
Let's uncover the reasons and signs of low testosterone with awareness.
Testosterone. The word makes us think of big muscles and loud voices, showing strength and dominance. But, this little molecule has more complex functions, hormone's most visible effect is undoubtedly on muscles and strength. It helps build proteins and fixes up muscles. This explains why men naturally carry more muscle mass than women, who have significantly lower testosterone levels. But beyond the gym, testosterone's influence extends to bone density , keeping our skeletons strong and resilient.
Intimacy is heavily influenced by testosterone. In men, it helps make sperm and affects sex drive. In women, it's involved in getting aroused. When testosterone levels drop, it can affect desires in both men and women.
This tiny chemical actually makes us feel calmer. It is a natural mood elevator that boosts confidence, motivation, and focus. Low levels may be linked to depression and anxiety.
Symptoms can vary, these are among the most common symptoms of low testosterone.
Usually, younger men are highly sexually active due to high testosterone. As we get older, especially after 30, testosterone levels start to go down. This drop might be linked to changes in sex drive and differences in erectile function. The decrease could be caused by various internal mechanisms that gradually change healthy testosterone levels by age.
The brain's small region, the hypothalamus, maintains healthy testosterone levels. It signals the pituitary gland, which communicates with testes (or ovaries in women), triggering testosterone production.
As age progresses, the communication network changes subtly. The hypothalamus signals less, weakening the pituitary's response, causing a drop in testosterone. Men see a 1-2% annual decline after 30, while women experience a sharper drop post-menopause.
The slowdown lacks a single cause but involves complex factors. In men, Leydig cells in testes decrease with age, and free testosterone diminishes, tightly binding to a protein (SHBG). This affects organs, leading to varied signs of testosterone hormone deficiency.
Hypogonadism means the gonads (ovaries or testes) don't function normally. It is an umbrella term that covers many hormonal imbalances, not just one disease. It messes up the harmony of sex hormones important for physical and mental well-being.
Due to its complex nature, diagnosing hypogonadism in male can be challenging due to overlapping symptoms with other conditions and the need for specialized tests.
In hypogonadism, the body produces less testosterone. The signals may be weak, the pituitary response slow, or the gonads might not work well, causing lower testosterone production.
Fertility challenges are common in both sexes due to the impact on egg and sperm production. Hypogonadism treatments can help with increasing sperm count and maintaining hormonal balance. Diagnosing hypogonadism involves a combination of medical history, physical examination, and laboratory tests.
Chronic conditions are one of the common causes of low testosterone. Some illnesses attack the testicles or ovaries, causing inflammation and hormone problems. Examples include lupus and infections like mumps or HIV. Several other conditions may mess up how the body makes and uses testosterone. Examples include obesity, diabetes, kidney and liver diseases, and HIV/AIDS.
Genetic disorders can also mess up how your body makes and uses testosterone:
Having an extra X chromosome (XXY) can lower testosterone. This affects puberty, muscle growth, and fertility. Examples include Klinefelter Syndrome.
Only having one X chromosome (X0) like in Turner Syndrome can lead to low hormone levels. This delays puberty, affects bone growth, and makes it hard to have babies.
A mutation in the brain called Kallmann Syndrome is also a part of testosterone disorders that can delay puberty and make it hard to conceive.
Faulty genes in the adrenal glands can mess up hormone production. This can cause problems with genitals and periods.
Some people's bodies with Androgen Insensitivity Syndrome (AIS) or other testosterone disorders can't use certain chemicals properly. This means they don't develop fully as expected during puberty.
Low hormonal activities may also be linked to chronic fatigue syndrome. Using testosterone replacement therapy or TRT for chronic illnesses is an effective method to naturally restore the chemical balance and treat the conditions. TRT for chronic illnesses is a complex and emerging field of research requiring careful consideration of potential benefits on a case-by-case basis.
Medications meant for pain relief, chronic conditions, or mental health can lower hormonal levels. For instance, pain relievers can temporarily affect the testicles' ability to make testosterone. Also, corticosteroids, often used for inflammation, can lower both male and female hormone production.
Antidepressants might change the signals that instruct the body to make hormones. This could affect how much of each hormone is made.
Some >cancer drugs make an enzyme called aromatase more active. Aromatase changes testosterone into estrogen, a different type of hormone. So, when aromatase is more active, there's less testosterone left in the blood.
Adding “medications for low t,” along with other treatments, can address all these symptoms.
Testosterone hormone deficiency isn't always the body's fault. Sometimes, there are other causes of low testosterone. Living an unhealthy lifestyle directly invites low testosterone levels. Here's how:
Constant stress messes with hormones. When you face ongoing mental or physical demands, the body boosts cortisol. This hormone, vital for stress coping, acts against testosterone, holding back its creation in testes' Leydig cells. So, ongoing stress can result in consistently low testosterone levels, showing up as less interest in sex, lower energy, and even muscle loss.
Your diet influences your body. Consuming processed foods, refined carbs, and unhealthy fats disrupts the metabolism. This can result in high blood sugar and resistance to insulin and impact the gonadal function. Additionally, not getting sufficient essential micronutrients like zinc and vitamin D worsens the situation.
Regular physical activity boosts testosterone. Lifting weights triggers Leydig cells to make testosterone by releasing luteinizing hormone (LH). Being inactive decreases LH and causes hormonal imbalance.
Drinking a bit may not affect testosterone much, but drinking too much can be bad. Alcohol messes up the brain function, making more cortisol and lowering testosterone. Too much alcohol can also directly hurt Leydig cells, making less testosterone. It may also cause hypogonadism in male.
Now that we understand the lifestyle factors that can influence hormonal balances, it's time to take action! Simple things can help in treating low testosterone in males and females:
Low testosterone lifestyle factors are multifaceted. Make these changes in daily life to make your body free from the symptoms. If things don't balance out or symptoms persist, you might need medical help for low testosterone treatment. Several treatments like hormone replacement therapy are tailored to suit individual needs and aim to bring the testosterone levels into balance.
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A. Symptoms like low libido, erectile dysfunction, chronic fatigue syndrome, muscle loss, and mood changes can be suggestive of low testosterone.
A. Yes, it is present in both men and women. In women, it is in low amounts and includes functions like controlling bone density, sex drive, and mood.
A. Suggests a complex relationship between testosterone and heart health. While high testosterone levels might be associated with an increased risk of certain cardiovascular issues, low levels may also raise risks.
A. Yes, it plays a vital role in sperm production. Low levels can lead to reduced sperm count and motility. However, hypogonadism treatments like testosterone replacement can also potentially increase sperm count.
A. Oral medications for low t are a common measure in treating low testosterone in males. However, like any medication, it can have potential side effects and risks. They should only be used under the supervision of a doctor. Never self-medicate as it can be harmful.
A. Low testosterone treatment depends on the cause, typically involving lifestyle changes, medications, or TRT (Testosterone Replacement Therapy) under medical supervision.
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