Why Storage Matters

Proper storage of prescription products helps maintain their stability. Products exposed to extreme conditions may become less effective or potentially unsafe. Following storage guidelines also helps reduce waste and maintain treatment continuity.

Unopened Pens: Keep Refrigerated

Unopened Ozempic pens should be stored in a refrigerator between 2°C and 8°C (36°F to 46°F) until their expiration date. They must never be frozen. If a pen has accidentally frozen, it should not be used and must be safely discarded.

To avoid accidental freezing, store the pens away from the cooling element of your fridge and monitor temperature regularly.

Opened Pens: Flexible Storage, but Use Within 56 Days

Once a pen has been opened, it can be stored either:

• At room temperature between 15°C and 30°C (59°F to 86°F)
• Or refrigerated between 2°C and 8°C (36°F to 46°F)

Regardless of your storage choice, the same pen must be discarded 56 days after first use—even if there’s still medication left.

Keep the cap on during storage, avoid exposure to heat or sunlight, and do not use a pen past its expiration date.

During Travel: Practical Tips

• Use an insulated case to protect from heat exposure.
• Do not leave pens in cars or checked luggage where temperatures may fluctuate.
• Store opened pens at room temperature, and unopened pens in a portable, temperature-controlled container.
• Avoid placing pens directly next to ice packs to prevent freezing.

If You Forgot to Refrigerate an Unopened Pen…

If an unopened pen has been left out of the fridge, check how long it was at room temperature. Extended exposure may reduce its quality, and it may no longer be suitable for use. Check the solution: it should be clear and colourless. If the product appears cloudy or contains particles, it should not be used.

When in doubt, consult a licensed healthcare professional for next steps.

Signs a Pen May Be Compromised

Before each use, inspect the solution. Discard the pen if you notice:

• Discolouration
• Cloudiness
• Floating particles
• Freezing (past or present)

Also, do not use a pen past its labeled expiration date or 56 days after opening, whichever comes first.

How to Dispose of an Expired Pen

Used or expired pens, along with used needles, should be placed in a secure sharps container. Follow your local pharmacy or municipal guidelines for medication and sharps disposal. Never throw loose pens or needles in household trash or recycling.

In Summary

• Refrigerate unopened pens between 2°C and 8°C.
• Use opened pens within 56 days, either refrigerated or at room temperature.
• Avoid freezing, excessive heat, or direct sunlight.
• Inspect pens before use for clarity and expiry.
• Consult your healthcare provider with any storage or usage questions.

For individuals undergoing weight management or chronic care plans, proper handling of medication—including storage—is a small but crucial part of ensuring the success and safety of treatment.