Written by
Science and Humans
Written by
Science and Humans
Medically approved by
Maria Jacob
Last updated
8/18/2025 5:30:00 AM
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Contrave and Saxenda are two prescription medications that may be prescribed as part of a weight-management plan. While both are used in similar contexts, they differ in composition, dosing, and other practical considerations. This guide provides a factual, balanced overview to help you understand their differences — not to promote one over the other.
Contrave contains a combination of bupropion and naltrexone.
Saxenda contains liraglutide.
Both are approved in Canada for weight management when used alongside a reduced-calorie diet and increased physical activity. The choice between them should be based on a discussion with a healthcare provider, considering your health profile, preferences, and treatment goals.
Contrave is available in tablet form, with dosing schedules determined by the prescribing provider.
Saxenda is provided in a pre-filled pen, with doses adjusted according to a gradual schedule set by the prescriber.
(Health Canada allows discussion of dosage formats but not administration instructions here.)
The cost for both medications can vary depending on dosage, pharmacy pricing, and insurance coverage. Some private insurance plans may cover one or both. Patients should check with their insurance provider and pharmacy for exact pricing.
Clinical studies have shown that both medications can support weight management when combined with healthy eating and exercise. The degree of effectiveness can vary from person to person. Neither is intended as a standalone solution — lifestyle modifications remain essential.
As prescription medications, both require monitoring by a healthcare provider. Your provider will evaluate potential benefits and risks based on your medical history and current health status.
There is no universal “better” option — the right choice depends on individual health factors, preferences, and how your body responds over time. Discussing your full health profile with your provider will ensure the safest and most effective approach.
Contrave and Saxenda are both Health Canada–approved prescription options for weight management, but they work differently and have different considerations. Always make decisions about medication in consultation with a licensed healthcare professional.
DisclaimerThis content is intended for educational purposes only and should not be interpreted as medical advice. Always consult a licensed healthcare provider for personalized recommendations. |
Contrave and Saxenda both have their own pros and cons. Which medication works on you the best depends on your age, lifestyle, dosage, diet, exercise schedule, etc. Consult a healthcare provider before you decide.
Yes, if you take the dosage as prescribed and pair it with a low-calorie diet and exercise. Most people observe weight loss of at least 5%, compared to what they started with, in 12 weeks of starting Contrave. If it does not work out for you, reconsider alternatives with a doctor.
The retail price of Contrave is approximately $438 for a month of tablets. However, the price of Contrave depends on which pharmacy you choose and your insurance policy. Remember to check with your insurance company.
Losing weight is a process. Contrave is a drug that aids in losing weight once paired with a low-calorie diet and sufficient exercise. You will observe weight loss soon, but it may not be significant for the first few weeks.
There are several side effects of Contrave which affect with varying intensity to different people. Some common side effects are vomiting, headaches, unusual dreams, dizziness, fatigue, nausea, constipation, etc. Usually, these affect you only temporarily. But if you observe serious side effects like increased heart rate, seizures, suicidal thoughts or behaviors, then contact your doctor immediately.
Weight loss depends on various factors like your lifestyle, diet, exercise schedule, dosage, etc. It is important to note that weight loss is a journey that takes time and determination. You should start seeing visible weight loss (upwards of 5% compared to the original weight) after 16 weeks of taking it as prescribed.
The retail price of Saxenda is approximately $1,635 for five 3ml pens. Note that the actual price you pay depends on the pharmacy you buy it from, your insurance policy, and the dosage.
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