How They Are Made

Bioidentical hormones are often created from plant-derived sources but are processed in laboratories to match human hormone structure. Synthetic hormones are also made in laboratories, but their molecular structure is not identical to naturally occurring hormones.

Compounded vs. Standardized Products

Standardized hormone products are manufactured in regulated doses. Compounded bioidentical hormones are prepared by pharmacists according to a healthcare provider’s prescription for an individual. Compounding allows for customization, but these products may not be subject to the same regulatory oversight as standardized versions. It’s important to ensure compounding is done by a licensed pharmacy using quality-controlled ingredients.

Key Differences

• Structure: Bioidentical hormones match human hormones; synthetic hormones differ in structure.
• Source: Bioidentical hormones are usually plant-derived; synthetic hormones may come from chemical or animal sources.
• Dosing: Synthetic hormones are available in fixed, regulated doses; bioidentical hormones may be standardized or compounded.

Considerations and Decision-Making

The choice between bioidentical and synthetic hormones depends on individual health needs, personal preferences, and professional medical advice. Factors that may be considered include:

• Medical history
• Current health status
• Age and stage of menopause
• Treatment goals

Only a qualified healthcare provider can determine which option, if any, is appropriate. Self-prescribing or adjusting hormone therapy without medical supervision is not recommended.

Myth: BHRT is “risk-free” because it is structurally similar to human hormones.
Fact: All hormone therapies may have potential risks and benefits, which should be reviewed with a healthcare provider.

Myth: Compounded formulations are automatically better.
Fact: Compounding is sometimes used for specific needs, but it does not inherently make a product safer or more effective.

Myth: Menopause symptoms in your forties are “too early” to address.
Fact: Menopausal symptoms can begin in the forties for many women. The decision to seek treatment is personal and should be guided by professional advice.

FAQ

Q: Which has fewer risks — BHRT or synthetic hormone therapy?

A: The potential benefits and risks vary for each individual. The decision should be made with a healthcare provider based on medical history, test results, and health goals.

Q: Are compounded BHRT formulations better than standardized synthetic hormones?

A: Not necessarily. Compounding is used for specific cases and must be prescribed by a qualified professional. Both compounded and standardized products have different oversight and quality considerations.

Q: I’m in my forties and experiencing menopausal symptoms — is this normal?

A: Yes, many women begin experiencing menopausal changes in their forties. A healthcare provider can help assess symptoms and discuss possible management options.